Molecular Biology of Archaea
We are interested in understanding the biogenesis of the archaeal cell envelope including processes like N-glycosylation, the assembly of macromolecular structures like pili and the archaellum, and regulatory processes depending on protein phosphorylation. We study these processes in two model archaea: the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius and the extremely halophilic euryarchaeon Haloferax volcanii.
We use genetic approaches to identify systems in Sulfolobus and Haloferax that are involved in the assembly of cell surface appendages and biochemically characterize the subunits and their interplay in the assembly process.
Our group is located at the Institute of Biology at the University of Freiburg in Southern Germany.
Solenne Ithurbide left the lab to start a new psotion with Yves Brun (Canada).
Sonja was elected into the Leopoldina, the Ntaional Academy of Science!
Nuno de Sousa Machado defends his thesis about the analysis of components of the archaellum motor complex.
Xing Ye leaves the lab for a Postdoctoral position in the lab of Martin Loose in Austria. All the best Xing!
Frank Braun defends his PhD thesis about second messengers in Haloferax volcanii.
Closed this year with an online Christmas party and pub quizz !
As numbers were going down, more people were allowed back into the lab. Work discussions still held online only.
Getting used to the online format: Phillip Nußbaum defends succesfully his PhD thesis !
Two new Postdocs, Solenne Ithurbide and Alejandra Recalde, started in the lab. We wish them all the best !
First online PhD defense with Zhengqun Li! Congrats !
People were allowed back into the lab in shifts, from this point on, wearing masks was (is) mandatory.
Due to the rise of the Corona virus, the lab closed down for three month and we only held online meetings.
Our paper on the structure and function of FlaF and FlaG in archaellum assembly and function was published in Nature Microbiology.
We received two grants from the Volkswagen-Foundation: the "Momentum" grant to work on cell division in archaea and the Life? consortium to work on the evolution of vesicle trafficking from archaea to eukaryotes.
Sonja Albers was elected as an EMBO member. See press release here.
We showed the existence of c-di-AMP and discuss its possible function in Haloferax volcanii in Franks's article.
We congratulate Tessa Quax, who got an Emmy-Noether-Fellowship to start her own lab on halophilic viruses of archaea! See her lab webpage here.
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