February 6, 2020

Euryarchaeal genomes encode di-adeylate cyclases (DacZ). We showed that H. volcanii produces c-di-AMP and that under the tested laboratory conditions it is essential as we could not delete the gene encoding dacZ.

A mutant which expressed lower amounts of dacZ showed no...

February 6, 2020

Although archaea use a totally different motility machinery than bacteria, eg. euryarchaea have obtained the full chemotaxis system from bacteria via horizontal gene transfer.

However, the archaellum has no FliM, to which CheY binds in bacteria. Therefore archaea have...

January 1, 2020

Archaea use a unique structure for swimming motility which is not hoomologous to bacterial flagella,  but instead resembles type IV pili. But in contrast to type IV pili, motion is not achieved by elongation and disassembly of the filament, but by rotation.

The smalles...

January 1, 2020

Almost all Sulfolobales contain an type IV pili operon named the UV inducible pilus operon (ups). This operon is highly induced after UV treatment of Sulfolobus cells or the occurence of DNA double strand breakages. As a result the cells express multiple pili all aroun...

January 1, 2019

Already in 2007 Zalan Szabo showed that archaellum expression in Sulfolobus solfataricus is starvation induced. Lateron we showed that the same is true for S. acidocaldarius, but nothing was known about the mechanims behind this regulatory process.

To date we have ident...

February 22, 2018

We studied how different Sulfolobus species form biofilms, how these are build and which components build their matrix. Moreover, we identified archaea specific regulators, the Lrs14 familiy, which are involved in the regulation of pathways that lead to biofilm formati...

February 20, 2016

Almost all extracellular proteins of archaea are modified by either N- or O-glycosylation or both. We have set out to analyze the N-glycosylation pathway in S. acidocaldarius and used the S-layer protein as a substrate protein. We identified a number of enzymes that pl...

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University of Freiburg

© 2019 by Sonja-Verena Albers.

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